J Emerg Nurs. 2025 Nov 27:S0099-1767(25)00454-4. Revista: 10.1016/j.jen.2025.10.025. Online ahead of print.

Spinal epidural hematoma is a rare but potentially devastating condition that can result in permanent neurologic deficits if not diagnosed promptly. This case report presents a 48-year-old female patient with a medical history of systemic lupus erythematosus, renal transplantation, and hypertension who developed spinal epidural hematoma after chiropractic manipulation, leading to acute quadriplegia. The objective of this report is to highlight the potential for spinal epidural hematoma development in patients with comorbidities or underlying risk factors, such as systemic autoimmune disease, hypertension, or organ transplantation, after chiropractic manipulation and to emphasize the importance of early recognition to prevent serious neurologic sequelae.

PubMed:41307523 | Revista:10.1016/j.jen.2025.10.025