Anaesth Crit Care Pain Med. 2025 Nov 26:101718. Revista: 10.1016/j.accpm.2025.101718. Online ahead of print.

OBJECTIVE: The French Society of Anaesthesia and Intensive Care (SFAR) and the French Society of Clinical Pharmacy (SFPC) have joined forces to propose recommendations for professional practice in the prevention of medication errors in anaesthesia and intensive care DESIGN: A group of 19 French experts from the French Society of Anaesthesia and Intensive Care (SFAR) and the French Society of Clinical Pharmacy (SFPC) was assembled. Potential conflicts of interest were formally declared at the outset of the recommendations development process, which was conducted independently of any industry funding. The authors followed the GRADE→ (Grading of Recommendations Assessment, Development and Evaluation) methodology to assess the level of evidence in the literature.

METHODS: 4 fields were defined: 1) Work environment and processes; 2) Human and organizational factors; 3) Post-hoc risk management; 4) The problem of drug shortages. For each field, the recommendations aimed to answer several questions formulated by the experts according to the PICO model (Population, Intervention, Comparison, Outcome). Based on these questions, an extensive 20-year bibliographic search was conducted, using predefined keywords in accordance with the PRISMA recommendations. Due to the very small number of studies that could provide the necessary power to answer the most important judgment criterion (i.e., medication errors), it was decided, prior to drafting the recommendations, to adopt the format of Professional Practice Guidelines (PPG) rather than Formalized Expert Recommendations. The recommendations were then voted on by all the experts using the GRADE grid method.

RESULTS: For all questions, recommendations could be formulated, either for the entire field of the question or partially. The EXPERT synthesis work and the application of the GRADE method resulted in 29 recommendations concerning the prevention of medication errors in anaesthesia and intensive care. After a round of voting and incorporating a few adjustments, a strong agreement was reached on all the recommendations.

CONCLUSION: There was strong agreement among the experts on providing recommendations aimed at preventing medication errors in anaesthesia and intensive care.

PubMed:41314385 | Revista:10.1016/j.accpm.2025.101718