J Burn Care Res. 2025 Nov 28:iraf222. doi: 10.1093/jbcr/iraf222. Online ahead of print.

Pyogenic granuloma (PG) is a benign vascular proliferation that commonly arises following trauma. Its occurrence in healing burn wounds, particularly in infants, is rare and poses diagnostic challenges. We present the case of an 11-month-old male who developed multiple rapidly growing, angiomatous nodules on the right cheek and scalp two weeks after sustaining a second-degree scald burn from boiling milk. The lesions exhibited typical bleeding and friability, prompting surgical excision and coverage with split-thickness skin grafts. Histopathological examination confirmed the diagnosis of PG. Postoperative recovery was uneventful, and follow-up at 2.5 years showed complete resolution without recurrence and minimal scarring. This case illustrates a rare but distinct manifestation of post-burn PG (PGB), emphasizing the importance of recognizing this reactive vascular phenomenon. A comprehensive review of the 38 cases reported in the literature so far underscores the variable clinical presentations and management strategies, reinforcing surgical excision as a reliable and curative intervention.

PubMed:41313237 | DOI:10.1093/jbcr/iraf222